Inhibition of HIF1α-Dependent Upregulation of Phospho-l-Plastin Resensitizes Multiple Myeloma Cells to Frontline Therapy

The introduction of novel frontline agents in multiple myeloma (MM), like immunomodulatory drugs and proteasome inhibitors, has improved the overall survival of patients. Yet, MM is still not curable, and drug resistance (DR) remains the main challenge. To improve the understanding of DR in MM, we e...

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Publicado no:Int J Mol Sci
Main Authors: Bosseler, Manon, Marani, Vanessa, Broukou, Angelina, Lequeux, Amandine, Kaoma, Tony, Schlesser, Vincent, François, Jean-Hugues, Palissot, Valérie, Berchem, Guy J., Aouali, Nasséra, Janji, Bassam
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6032243/
https://ncbi.nlm.nih.gov/pubmed/29882856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19061551
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