A mutation of the glucocorticoid receptor in primary cortisol resistance.

The precise molecular abnormalities that cause primary cortisol resistance have not been completely described. In a subject with primary cortisol resistance we have observed glucocorticoid receptors (hGR) with a decreased affinity for dexamethasone. We hypothesize that a mutation of the hGR glucocor...

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Autors principals: Malchoff, D M, Brufsky, A, Reardon, G, McDermott, P, Javier, E C, Bergh, C H, Rowe, D, Malchoff, C D
Format: Artigo
Idioma:Inglês
Publicat: 1993
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC288186/
https://ncbi.nlm.nih.gov/pubmed/7683692
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