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Molecular Identification of NAT8 as the Enzyme That Acetylates Cysteine S-Conjugates to Mercapturic Acids

Our goal was to identify the reaction catalyzed by NAT8 (N-acetyltransferase 8), a putative N-acetyltransferase homologous to the enzyme (NAT8L) that produces N-acetylaspartate in brain. The almost exclusive expression of NAT8 in kidney and liver and its predicted association with the endoplasmic re...

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Detalhes bibliográficos
Main Authors: Veiga-da-Cunha, Maria, Tyteca, Donatienne, Stroobant, Vincent, Courtoy, Pierre J., Opperdoes, Fred R., Van Schaftingen, Emile
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881811/
https://ncbi.nlm.nih.gov/pubmed/20392701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.110924
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