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Metabolite Proofreading in Carnosine and Homocarnosine Synthesis: MOLECULAR IDENTIFICATION OF PM20D2 AS β-ALANYL-LYSINE DIPEPTIDASE

Carnosine synthase is the ATP-dependent ligase responsible for carnosine (β-alanyl-histidine) and homocarnosine (γ-aminobutyryl-histidine) synthesis in skeletal muscle and brain, respectively. This enzyme uses, also at substantial rates, lysine, ornithine, and arginine instead of histidine, yet the...

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書誌詳細
主要な著者: Veiga-da-Cunha, Maria, Chevalier, Nathalie, Stroobant, Vincent, Vertommen, Didier, Van Schaftingen, Emile
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4094082/
https://ncbi.nlm.nih.gov/pubmed/24891507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.576579
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