Parkinson Disease-associated DJ-1 Is Required for the Expression of the Glial Cell Line-derived Neurotrophic Factor Receptor RET in Human Neuroblastoma Cells

Mutations in PARK7/DJ-1 are associated with autosomal recessive, early onset Parkinson disease (PD). DJ-1 is an atypical peroxiredoxin-like peroxidase that may act as a redox-dependent chaperone and a regulator of transcription. Here we show that DJ-1 plays an essential role in the expression of rea...

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Bibliographische Detailangaben
Hauptverfasser: Foti, Rossana, Zucchelli, Silvia, Biagioli, Marta, Roncaglia, Paola, Vilotti, Sandra, Calligaris, Raffaella, Krmac, Helena, Girardini, Javier Enrique, Del Sal, Giannino, Gustincich, Stefano
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2010
Schlagworte:
Molecular Bases of Disease
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881782/
https://ncbi.nlm.nih.gov/pubmed/20395301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.088294
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