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The PML nuclear bodies-associated protein TTRAP regulates ribosome biogenesis in nucleolar cavities upon proteasome inhibition

TRAF and TNF receptor-associated protein (TTRAP) is a multifunctional protein that can act in the nucleus as a 5′-tyrosyl DNA phosphodiesterase and in the cytoplasm as a regulator of cell signaling. In this paper we show that in response to proteasome inhibition TTRAP accumulates in nucleolar caviti...

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Bibliografiske detaljer
Main Authors: Vilotti, S, Biagioli, M, Foti, R, Dal Ferro, M, Lavina, Z Scotto, Collavin, L, Del Sal, G, Zucchelli, S, Gustincich, S
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3278732/
https://ncbi.nlm.nih.gov/pubmed/21921940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2011.118
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