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Aldehyde Dehydrogenase 7A1 (ALDH7A1) Is a Novel Enzyme Involved in Cellular Defense against Hyperosmotic Stress

Mammalian ALDH7A1 is homologous to plant ALDH7B1, an enzyme that protects against various forms of stress, such as salinity, dehydration, and osmotic stress. It is known that mutations in the human ALDH7A1 gene cause pyridoxine-dependent and folic acid-responsive seizures. Herein, we show for the fi...

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Main Authors: Brocker, Chad, Lassen, Natalie, Estey, Tia, Pappa, Aglaia, Cantore, Miriam, Orlova, Valeria V., Chavakis, Triantafyllos, Kavanagh, Kathryn L., Oppermann, Udo, Vasiliou, Vasilis
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2010
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881771/
https://ncbi.nlm.nih.gov/pubmed/20207735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.077925
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