Aldehyde Dehydrogenase 7A1 (ALDH7A1) Is a Novel Enzyme Involved in Cellular Defense against Hyperosmotic Stress

Mammalian ALDH7A1 is homologous to plant ALDH7B1, an enzyme that protects against various forms of stress, such as salinity, dehydration, and osmotic stress. It is known that mutations in the human ALDH7A1 gene cause pyridoxine-dependent and folic acid-responsive seizures. Herein, we show for the fi...

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Detalhes bibliográficos
Main Authors: Brocker, Chad, Lassen, Natalie, Estey, Tia, Pappa, Aglaia, Cantore, Miriam, Orlova, Valeria V., Chavakis, Triantafyllos, Kavanagh, Kathryn L., Oppermann, Udo, Vasiliou, Vasilis
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881771/
https://ncbi.nlm.nih.gov/pubmed/20207735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.077925
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