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Amino Acid Residue Val(362) Plays a Critical Role in Maintaining the Structure of C Terminus of Connexin 50 and in Lens Epithelial-fiber Differentiation

We have previously shown that connexin (Cx) 50, unlike the other two lens connexins, Cx43 and Cx46, promotes chicken lens epithelial-fiber differentiation in a channel-independent manner. Here, we show that deletion of the PEST motif at the C terminus (CT) domain of Cx50 attenuates the stimulatory e...

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Detalhes bibliográficos
Main Authors: Shi, Qian, Banks, Eric A., Yu, X. Sean, Gu, Sumin, Lauer, Janelle, Fields, Gregg B., Jiang, Jean X.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881767/
https://ncbi.nlm.nih.gov/pubmed/20395299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.107052
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