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Extended N-Sulfated Domains Reside at the Nonreducing End of Heparan Sulfate Chains

Heparan sulfate (HS) serves as a cell-surface co-receptor for growth factors, morphogens, and chemokines. These HS and protein binding events depend on the fine structure and distribution of domains along an HS chain. A given domain can vary in terms of uronic acid epimer, N- and O-sulfate, and N-ac...

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Détails bibliographiques
Auteurs principaux: Staples, Gregory O., Shi, Xiaofeng, Zaia, Joseph
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881759/
https://ncbi.nlm.nih.gov/pubmed/20363743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.101592
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