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Differential Induction of Interleukin-10 in Monocytes by HIV-1 Clade B and Clade C Tat Proteins

The clade B human immunodeficiency virus, type 1 (HIV-1) Tat (trans-acting regulatory protein) induces interleukin-10 (IL-10) production in monocytes. IL-10, an anti-inflammatory cytokine, down-regulates proinflammatory cytokines and suppresses the immune response, leading to a rapid progression fro...

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Detalhes bibliográficos
Main Authors: Wong, Justine K., Campbell, Grant R., Spector, Stephen A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881757/
https://ncbi.nlm.nih.gov/pubmed/20378550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.120840
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