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Mechanism of HIV-1-TAT Induction of Interleukin-1β from Human Monocytes: Involvement of the Phospholipase C/Protein Kinase C Signaling Cascade

Human immunodeficiency virus TAT plays an important role in the dysregulation of cytokine production associated with the neurological disorders that follow HIV infection. IL-1β is one of the important inflammatory cytokines secreted by immune-activated monocytes/macrophages. Previous reports have sh...

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Autors principals: Yang, Yongbo, Wu, Jianguo, Lu, Yuanan
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849807/
https://ncbi.nlm.nih.gov/pubmed/20336759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jmv.21720
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