The Calcium-mobilizing Messenger Nicotinic Acid Adenine Dinucleotide Phosphate Participates in Sperm Activation by Mediating the Acrosome Reaction

Before a sperm can fertilize an egg it must undergo a final activation step induced by the egg termed the acrosome reaction. During the acrosome reaction a lysosome-related organelle, the acrosome, fuses with the plasma membrane to release hydrolytic enzymes and expose an egg-binding protein. Becaus...

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Main Authors: Vasudevan, Sridhar R., Lewis, Alexander M., Chan, Jennifer W., Machin, Claire L., Sinha, Debroshi, Galione, Antony, Churchill, Grant C.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2010
Teme:
Signal Transduction
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881750/
https://ncbi.nlm.nih.gov/pubmed/20400502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.087858
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