Cytolethal Distending Toxin Family Members Are Differentially Affected by Alterations in Host Glycans and Membrane Cholesterol

Cytolethal distending toxins (CDTs) are tripartite protein exotoxins produced by a diverse group of pathogenic Gram-negative bacteria. Based on their ability to induce DNA damage, cell cycle arrest, and apoptosis of cultured cells, CDTs are proposed to enhance virulence by blocking cellular division...

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Detalhes bibliográficos
Main Authors: Eshraghi, Aria, Maldonado-Arocho, Francisco J., Gargi, Amandeep, Cardwell, Marissa M., Prouty, Michael G., Blanke, Steven R., Bradley, Kenneth A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881744/
https://ncbi.nlm.nih.gov/pubmed/20385557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.112912
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