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Effects of the Melatonin MT-1/MT-2 Agonist Ramelteon on Daytime Body Temperature and Sleep

STUDY OBJECTIVES: A reduction in core temperature and an increase in the distal-proximal skin gradient (DPG) are reported to be associated with shorter sleep onset latencies (SOL) and better sleep quality. Ramelteon is a melatonin MT-1/MT-2 agonist approved for the treatment of insomnia. At night, r...

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Detalhes bibliográficos
Main Authors: Markwald, Rachel R., Lee-Chiong, Teofilo L., Burke, Tina M., Snider, Jesse A., Wright, Kenneth P.
Formato: Artigo
Idioma:Inglês
Publicado em: Associated Professional Sleep Societies, LLC 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881716/
https://ncbi.nlm.nih.gov/pubmed/20550024
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