Chronic growth hormone (GH) hypersecretion induces reciprocal and reversible changes in mRNA levels from hypothalamic GH-releasing hormone and somatostatin neurons in the rat.

Effects of growth hormone (GH) hypersecretion on somatostatin-(SRIH) and GH-releasing hormone (GHRH) were studied by in situ hybridization and receptor autoradiography in rats bearing a GH-secreting tumor. 6 and 18 wk after tumor induction, animals displayed a sharp increase in body weight and GH pl...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Autores principales: Bertherat, J, Timsit, J, Bluet-Pajot, M T, Mercadier, J J, Gourdji, D, Kordon, C, Epelbaum, J
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 1993
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC288159/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8097209/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116389
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