Effects of chronic growth hormone hypersecretion on intrinsic contractility, energetics, isomyosin pattern, and myosin adenosine triphosphatase activity of rat left ventricle.

We studied papillary muscle mechanics and energetics, myosin phenotype, and ATPase activities in left ventricles from rats bearing a growth hormone (GH)--secreting tumor. 18 wk after tumor induction, animals exhibited a dramatic increase in body weight (+101% vs. controls) but no change in the ventr...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Timsit, J, Riou, B, Bertherat, J, Wisnewsky, C, Kato, N S, Weisberg, A S, Lubetzki, J, Lecarpentier, Y, Winegrad, S, Mercadier, J J
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1990
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296753/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2143510/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114737
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