Effects of chronic growth hormone hypersecretion on intrinsic contractility, energetics, isomyosin pattern, and myosin adenosine triphosphatase activity of rat left ventricle.

We studied papillary muscle mechanics and energetics, myosin phenotype, and ATPase activities in left ventricles from rats bearing a growth hormone (GH)--secreting tumor. 18 wk after tumor induction, animals exhibited a dramatic increase in body weight (+101% vs. controls) but no change in the ventr...

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Vydáno v:J Clin Invest
Hlavní autoři: Timsit, J, Riou, B, Bertherat, J, Wisnewsky, C, Kato, N S, Weisberg, A S, Lubetzki, J, Lecarpentier, Y, Winegrad, S, Mercadier, J J
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 1990
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296753/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2143510/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114737
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