Neurotrophin-3 Is a Novel Angiogenic Factor Capable of Therapeutic Neovascularization in a Mouse Model of Limb Ischemia

OBJECTIVE: To investigate the novel hypothesis that neurotrophin-3 (NT-3), an established neurotrophic factor that participates in embryonic heart development, promotes blood vessel growth. METHODS AND RESULTS: We evaluated the proangiogenic capacity of recombinant NT-3 in vitro and of NT-3 gene tra...

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Main Authors: Cristofaro, Brunella, Stone, Oliver A., Caporali, Andrea, Dawbarn, David, Ieronimakis, Nicholas, Reyes, Morayma, Madeddu, Paolo, Bates, David O., Emanueli, Costanza
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881585/
https://ncbi.nlm.nih.gov/pubmed/20360537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.109.205468
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