The neurotrophin receptor p75(NTR) triggers endothelial cell apoptosis and inhibits angiogenesis: implications for diabetes-induced impairment of reparative neovascularization

Diabetes compromises endothelial function and inhibits reparative neovascularization. The neurotrophin receptor p75(NTR) is scarcely present in healthy endothelial cells (EC), but diabetes induces p75(NTR) in capillary EC of ischemic limb muscles. Here, we show that forced p75(NTR) expression impair...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Caporali, Andrea, Pani, Elisabetta, Horrevoets, Anton J. G., Kraenkel, Nicolle, Oikawa, Atsuhiko, Sala-Newby, Graciela B., Meloni, Marco, Cristofaro, Brunella, Graiani, Gallia, Leroyer, Aurelie, Boulanger, Chantal, Herman, Andrew, Spinetti, Gaia, Yoon, Sung Ok, Madeddu, Paolo, Emanueli, Costanza
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2008
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2640941/
https://ncbi.nlm.nih.gov/pubmed/18566344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.108.177386
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