The neurotrophin receptor p75(NTR) triggers endothelial cell apoptosis and inhibits angiogenesis: implications for diabetes-induced impairment of reparative neovascularization

Diabetes compromises endothelial function and inhibits reparative neovascularization. The neurotrophin receptor p75(NTR) is scarcely present in healthy endothelial cells (EC), but diabetes induces p75(NTR) in capillary EC of ischemic limb muscles. Here, we show that forced p75(NTR) expression impair...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Caporali, Andrea, Pani, Elisabetta, Horrevoets, Anton J. G., Kraenkel, Nicolle, Oikawa, Atsuhiko, Sala-Newby, Graciela B., Meloni, Marco, Cristofaro, Brunella, Graiani, Gallia, Leroyer, Aurelie, Boulanger, Chantal, Herman, Andrew, Spinetti, Gaia, Yoon, Sung Ok, Madeddu, Paolo, Emanueli, Costanza
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2640941/
https://ncbi.nlm.nih.gov/pubmed/18566344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.108.177386
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge