Antiretroviral drugs for preventing mother-to-child transmission of HIV in sub-Saharan Africa: Balancing efficacy and infant toxicity

OBJECTIVE: Antiretroviral drugs (ARVs) can prevent HIV mother-to-child transmission (PMTCT), but in utero ARV exposure may be associated with neurologic symptoms due to mitochondrial toxicity (MT). We sought to identify the currently recommended PMTCT regimen that optimally balances risks of pediatr...

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Main Authors: Ciaranello, Andrea L., Seage, George R., Freedberg, Kenneth A., Weinstein, Milton C., Lockman, Shahin, Walensky, Rochelle P.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881583/
https://ncbi.nlm.nih.gov/pubmed/18981776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0b013e3283189bd7
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