Associations of Chemokine Receptor Polymorphisms With HIV-1 Mother-to-Child Transmission in Sub-Saharan Africa: Possible Modulation of Genetic Effects by Antiretrovirals

BACKGROUND: HIV-1 mother-to-child transmission (MTCT) remains an important route of infection in sub-Saharan Africa. METHODS: Genetic variants in CCR5 promoter, CCR2, CX(3)CR1, and Stromal cell-derived factor-1 (SDF-1) genes were determined in 980 infants from sub-Saharan Africa using real-time poly...

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Main Authors: Singh, Kumud K., Hughes, Michael D., Chen, Jie, Phiri, Kelesitse, Rousseau, Christine, Kuhn, Louise, Coutsoudis, Anna, Jackson, J. Brooks, Guay, Laura A., Musoke, Philippa, Mmiro, Francis, Semba, Richard D., Spector, Stephen A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2748918/
https://ncbi.nlm.nih.gov/pubmed/18845960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0b013e318186eaa4
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