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Development of a Bioassay for Detection of Wnt-Binding Affinities for Individual Frizzled Receptors

Wnts are secreted lipid-modified glycoproteins that carry out various signaling functions during development and in adult tissue. Wnt signaling is mediated by Fzd receptors at the cell surface and can be modulated by the secreted frizzled related proteins (SFRPs) and other molecular antagonists. Abn...

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Autores principales: Carmon, Kendra S., Loose, David S.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881539/
https://ncbi.nlm.nih.gov/pubmed/20227380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2010.03.009
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