Enhanced LH action in transgenic female mice expressing hCGβ-subunit induces pituitary prolactinomas; the role of high progesterone levels

The etiology of pituitary adenomas remains largely unknown, with the exception of involvement of estrogens in the formation of prolactinomas. We have examined the molecular pathogenesis of prolactin-producing pituitary adenomas in transgenic female mice expressing the human choriongonadotropin (hCG)...

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Detalhes bibliográficos
Main Authors: Ahtiainen, Petteri, Sharp, Victoria, Rulli, Susana B, Rivero-Müller, Adolfo, Mamaeva, Veronika, Röyttä, Matias, Huhtaniemi, Ilpo
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Endocrinology 2010
Assuntos:
Regular Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881531/
https://ncbi.nlm.nih.gov/pubmed/20453081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1677/ERC-10-0016
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