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Effect of excess alpha-hemoglobin chains on cellular and membrane oxidation in model beta-thalassemic erythrocytes.

While red cells from individuals with beta thalassemias are characterized by evidence of elevated in vivo oxidation, it has not been possible to directly examine the relationship between excess alpha-hemoglobin chains and the observed oxidant damage. To investigate the oxidative effects of unpaired...

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Опубликовано в::J Clin Invest
Главные авторы: Scott, M D, van den Berg, J J, Repka, T, Rouyer-Fessard, P, Hebbel, R P, Beuzard, Y, Lubin, B H
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 1993
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC288150/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7682576/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116380
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