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CpG-ODN 2006 and human parvovirus B19 genome consensus sequences selectively inhibit growth and development of erythroid progenitor cells

Recent studies have shown that anemia is commonly observed after exposure to pathogens or pathogen-derived products, which are recognized via Toll-like receptor 9 (TLR9). In the current study, we demonstrate that CpG oligodeoxynucleotide-2006, a TLR9 ligand with phosphodiester (PO; 2006-PO) but not...

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Detalhes bibliográficos
Main Authors: Guo, Yong-Mei, Ishii, Keiko, Hirokawa, Makoto, Tagawa, Hiroyuki, Ohyagi, Hideaki, Michishita, Yoshihiro, Ubukawa, Kumi, Yamashita, Junsuke, Ohteki, Toshiaki, Onai, Nobuyuki, Kawakami, Kazuyoshi, Xiao, Weiguo, Sawada, Kenichi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881496/
https://ncbi.nlm.nih.gov/pubmed/20348392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-08-239202
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