The post sepsis-induced expansion and enhanced function of regulatory T cells create an environment to potentiate tumor growth

One of the more insidious outcomes of patients who survive severe sepsis is profound immunosuppression. In this study, we addressed the hypothesis that post septic immune defects were due, in part, to the presence and/or expansion of regulatory T cells (Tregs). After recovery from severe sepsis, mic...

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Hauptverfasser: Cavassani, Karen A., Carson, William F., Moreira, Ana Paula, Wen, Haitao, Schaller, Matthew A., Ishii, Makoto, Lindell, Dennis M., Dou, Yali, Lukacs, Nicholas W., Keshamouni, Venkateshwar G., Hogaboam, Cory M., Kunkel, Steven L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2010
Schlagworte:
Immunobiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881495/
https://ncbi.nlm.nih.gov/pubmed/20130237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-09-241083
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