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Assessing the functional coherence of gene sets with metrics based on the Gene Ontology graph

Motivation: The results of initial analyses for many high-throughput technologies commonly take the form of gene or protein sets, and one of the ensuing tasks is to evaluate the functional coherence of these sets. The study of gene set function most commonly makes use of controlled vocabulary in the...

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Detalhes bibliográficos
Main Authors: Richards, Adam J., Muller, Brian, Shotwell, Matthew, Cowart, L. Ashley, Rohrer, Bäerbel, Lu, Xinghua
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881388/
https://ncbi.nlm.nih.gov/pubmed/20529941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btq203
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