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Self-assembly behaviour of colistin and its prodrug colistin methanesulfonate: implications for solution stability and solubilization

Colistin is an amphiphilic antibiotic that has re-emerged into clinical use due to the increasing prevalence of difficult-to-treat Gram-negative infections. The existence of self-assembling colloids in solutions of colistin and its derivative prodrug, colistin methanesulfonate (CMS) was investigated...

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Main Authors: Wallace, Stephanie J., Li, Jian, Nation, Roger L., Prankerd, Richard J., Velkov, Tony, Boyd, Ben J.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881163/
https://ncbi.nlm.nih.gov/pubmed/20302384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp100458x
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