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Decreased Energy Metabolism Extends Life Span in Caenorhabditis elegans Without Reducing Oxidative Damage

On the basis of the free radical and rate of living theories of aging, it has been proposed that decreased metabolism leads to increased longevity through a decreased production of reactive oxygen species (ROS). In this article, we examine the relationship between mitochondrial energy metabolism and...

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Autores principales: Van Raamsdonk, Jeremy Michael, Meng, Yan, Camp, Darius, Yang, Wen, Jia, Xihua, Bénard, Claire, Hekimi, Siegfried
Formato: Artigo
Lenguaje:Inglês
Publicado: Genetics Society of America 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881137/
https://ncbi.nlm.nih.gov/pubmed/20382831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.110.115378
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