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Decreased Energy Metabolism Extends Life Span in Caenorhabditis elegans Without Reducing Oxidative Damage

On the basis of the free radical and rate of living theories of aging, it has been proposed that decreased metabolism leads to increased longevity through a decreased production of reactive oxygen species (ROS). In this article, we examine the relationship between mitochondrial energy metabolism and...

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Главные авторы: Van Raamsdonk, Jeremy Michael, Meng, Yan, Camp, Darius, Yang, Wen, Jia, Xihua, Bénard, Claire, Hekimi, Siegfried
Формат: Artigo
Язык:Inglês
Опубликовано: Genetics Society of America 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881137/
https://ncbi.nlm.nih.gov/pubmed/20382831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.110.115378
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