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Distinct Regulation of Mlh1p Heterodimers in Meiosis and Mitosis in Saccharomyces cerevisiae

Mlh1p forms three heterodimers that are important for mismatch repair (Mlh1p/Pms1p), crossing over during meiosis (Mlh1p/Mlh3p), and channeling crossover events into a specific pathway (Mlh1p/Mlh2p). All four proteins contain highly conserved ATPase domains and Pms1p has endonuclease activity. Studi...

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Библиографические подробности
Главные авторы: Cotton, Victoria E., Hoffmann, Eva R., Borts, Rhona H.
Формат: Artigo
Язык:Inglês
Опубликовано: Genetics Society of America 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881129/
https://ncbi.nlm.nih.gov/pubmed/20382827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.110.116806
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