Molecular mechanism of chemoresistance by miR-215 in osteosarcoma and colon cancer cells

BACKGROUND: Translational control mediated by non-coding microRNAs (miRNAs) plays a key role in the mechanism of cellular resistance to anti-cancer drug treatment. Dihydrofolate reductase (DHFR) and thymidylate synthase (TYMS, TS) are two of the most important targets for antifolate- and fluoropyrim...

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Autori principali: Song, Bo, Wang, Yuan, Titmus, Matthew A, Botchkina, Galina, Formentini, Andrea, Kornmann, Marko, Ju, Jingfang
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2010
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881118/
https://ncbi.nlm.nih.gov/pubmed/20433742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-96
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