MicroRNA-101 negatively regulates Ezh2 and its expression is modulated by androgen receptor and HIF-1α/HIF-1β

BACKGROUND: In prostate cancer (PCa), the common treatment involving androgen ablation alleviates the disease temporarily, but results in the recurrence of highly aggressive and androgen-independent metastatic cancer. Therefore, more effective therapeutic approaches are needed. It is known that aber...

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Main Authors: Cao, Paul, Deng, Zhiyong, Wan, Meimei, Huang, Weiwei, Cramer, Scott D, Xu, Jianfeng, Lei, Ming, Sui, Guangchao
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2010
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881117/
https://ncbi.nlm.nih.gov/pubmed/20478051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-108
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