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Performance in population models for count data, part II: a new SAEM algorithm

Analysis of count data from clinical trials using mixed effect analysis has recently become widely used. However, algorithms available for the parameter estimation, including LAPLACE and Gaussian quadrature (GQ), are associated with certain limitations, including bias in parameter estimates and the...

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Autors principals: Savic, Radojka, Lavielle, Marc
Format: Artigo
Idioma:Inglês
Publicat: Springer 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881036/
https://ncbi.nlm.nih.gov/pubmed/19680795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10928-009-9127-7
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