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LINE-1 methylation is inherited in familial testicular cancer kindreds

BACKGROUND: Testicular germ cell tumors (TGCT) are the most frequent cancers among young men. There is a clear familial component to TGCT etiology, but no high-penetrance susceptibility gene has been identified. Epigenetic aberrations of the genome represent an alternative mechanism for cancer susce...

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Detalhes bibliográficos
Main Authors: Mirabello, Lisa, Savage, Sharon A, Korde, Larissa, Gadalla, Shahinaz M, Greene, Mark H
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2880977/
https://ncbi.nlm.nih.gov/pubmed/20478068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-11-77
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