LINE-1 methylation is inherited in familial testicular cancer kindreds

BACKGROUND: Testicular germ cell tumors (TGCT) are the most frequent cancers among young men. There is a clear familial component to TGCT etiology, but no high-penetrance susceptibility gene has been identified. Epigenetic aberrations of the genome represent an alternative mechanism for cancer susce...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Mirabello, Lisa, Savage, Sharon A, Korde, Larissa, Gadalla, Shahinaz M, Greene, Mark H
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2010
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2880977/
https://ncbi.nlm.nih.gov/pubmed/20478068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-11-77
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