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The histone chaperone Nap1 promotes nucleosome assembly by eliminating non-nucleosomal histone DNA interactions

The organization of the eukaryotic genome into nucleosomes dramatically impacts the regulation of gene expression. The delicate balance between transcription and DNA compaction relies heavily on nucleosome dynamics. Surprisingly, little is known about the free energy required to assemble these large...

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Autors principals: Andrews, Andrew J., Chen, Xu, Zevin, Alexander, Stargell, Laurie A., Luger, Karolin
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2880918/
https://ncbi.nlm.nih.gov/pubmed/20347425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.01.037
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