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Chaperone Nap1 shields histone surfaces used in a nucleosome and can put H2A-H2B in an unconventional tetrameric form

The histone H2A-H2B heterodimer is an integral component of the nucleosome. The cellular localization and deposition of H2A-H2B into chromatin is regulated by numerous factors including histone chaperones such as Nucleosome Assembly Protein 1 (Nap1). We use hydrogen-deuterium exchange coupled to mas...

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Hlavní autoři: D’Arcy, Sheena, Martin, Kyle W., Panchenko, Tanya, Chen, Xu, Bergeron, Serge, Stargell, Laurie A., Black, Ben E., Luger, Karolin
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3878309/
https://ncbi.nlm.nih.gov/pubmed/23973327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.07.015
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