DNA damage responses by human ELG1 in S phase are important to maintain genomic integrity

Genomic integrity depends on DNA replication, recombination and repair, particularly in S phase. We demonstrate that a human homologue of yeast Elg1 plays an important role in S phase to preserve genomic stability. The level of ELG1 is induced during recovery from a variety of DNA damage. In respons...

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Hauptverfasser: Sikdar, Nilabja, Banerjee, Soma, Lee, Kyoo-young, Wincovitch, Stephen, Pak, Evgenia, Nakanishi, Koji, Jasin, Maria, Dutra, Amalia, Myung, Kyungjae
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2880862/
https://ncbi.nlm.nih.gov/pubmed/19755857
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