Iron uptake from plasma transferrin by a transferrin receptor 2 mutant mouse model of haemochromatosis

BACKGROUND & AIMS: Hereditary haemochromatosis type 3 is caused by mutations in transferrin receptor (TFR) 2. TFR2 has been shown to mediate iron transport in vitro and regulate iron homeostasis. The aim of this study was to determine the role of Tfr2 in iron transport in vivo using a Tfr2 mutan...

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Main Authors: Chua, Anita C.G., Delima, Roheeth D., Morgan, Evan H., Herbison, Carly E., Tirnitz-Parker, Janina E.E., Graham, Ross M., Fleming, Robert E., Britton, Robert S., Bacon, Bruce R., Olynyk, John K., Trinder, Debbie
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2880807/
https://ncbi.nlm.nih.gov/pubmed/20133002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2009.12.010
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