Solution Structure and Characterisation of the Human Pyruvate Dehydrogenase Complex Core Assembly

Mammalian pyruvate dehydrogenase complex (PDC) is a key multi-enzyme assembly that is responsible for glucose homeostasis maintenance and conversion of pyruvate into acetyl-CoA. It comprises a central pentagonal dodecahedral core consisting of two subunit types (E2 and E3BP) to which peripheral enzy...

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Main Authors: Vijayakrishnan, S., Kelly, S.M., Gilbert, R.J.C., Callow, P., Bhella, D., Forsyth, T., Lindsay, J.G., Byron, O.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2880790/
https://ncbi.nlm.nih.gov/pubmed/20361979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.03.043
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