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A Novel Method Combining Linkage Disequilibrium Information and Imputed Functional Knowledge for tagSNP Selection

Analyses of high-density SNPs in genetic studies have the potential problems of prohibitive genotyping costs and inflated false discovery rates. Current methods select subsets of representative SNPs (tagSNPs) using information either on potential biologic functionality of the SNPs or on the underlyi...

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Detalhes bibliográficos
Main Authors: Rochat, R.H., de las Fuentes, L., Stormo, G., Davila-Roman, V.G., Charles Gu, C.
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2880730/
https://ncbi.nlm.nih.gov/pubmed/17587853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000104227
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