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Markov Models for Inferring Copy Number Variations from Genotype Data on Illumina Platforms
BACKGROUND/AIMS: Illumina genotyping arrays provide information on DNA copy number. Current methodology for their analysis assumes linkage equilibrium across adjacent markers. This is unrealistic, given the markers high density, and can result in reduced specificity. Another limitation of current me...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
S. Karger AG
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2880724/ https://ncbi.nlm.nih.gov/pubmed/19339782 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000210445 |
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