Age-related susceptibility to severe malaria associated with galectin-2 in highland Papuans

BACKGROUND: Age and host genetics are important determinants of malaria severity. Lymphotoxin-alpha (LTα) has been linked to the development of cerebral malaria (CM) and other severe malaria (SM) syndromes. Mutations in genes regulating LTα production contribute to other acute vascular diseases and...

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Autores principales: Randall, Louise M., Kenangalem, Enny, Lampah, Daniel A, Tjitra, Emiliana, Mwaikambo, Esther D, Handojo, Tjandra, Piera, Kim A, Zhao, Zhen Zhen, de Labastida Rivera, Fabian, Zhou, Yonghong, McSweeney, Karli M., Le, Lien, Amante, Fiona H., Haque, Ashraful, Stanley, Amanda C., Woodberry, Tonia, Salwati, Ervi, Granger, Donald L, Hobbs, Maurine R, Price, Ric N., Weinberg, J Brice, Montgomery, Grant W., Anstey, Nicholas M., Engwerda, Christian R.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2880661/
https://ncbi.nlm.nih.gov/pubmed/20500087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/653125
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