Age-related susceptibility to severe malaria associated with galectin-2 in highland Papuans

BACKGROUND: Age and host genetics are important determinants of malaria severity. Lymphotoxin-alpha (LTα) has been linked to the development of cerebral malaria (CM) and other severe malaria (SM) syndromes. Mutations in genes regulating LTα production contribute to other acute vascular diseases and...

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Main Authors: Randall, Louise M., Kenangalem, Enny, Lampah, Daniel A, Tjitra, Emiliana, Mwaikambo, Esther D, Handojo, Tjandra, Piera, Kim A, Zhao, Zhen Zhen, de Labastida Rivera, Fabian, Zhou, Yonghong, McSweeney, Karli M., Le, Lien, Amante, Fiona H., Haque, Ashraful, Stanley, Amanda C., Woodberry, Tonia, Salwati, Ervi, Granger, Donald L, Hobbs, Maurine R, Price, Ric N., Weinberg, J Brice, Montgomery, Grant W., Anstey, Nicholas M., Engwerda, Christian R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2880661/
https://ncbi.nlm.nih.gov/pubmed/20500087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/653125
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