Human T cell recognition of the blood stage antigen Plasmodium hypoxanthine guanine xanthine phosphoribosyl transferase (HGXPRT) in acute malaria

BACKGROUND: The Plasmodium purine salvage enzyme, hypoxanthine guanine xanthine phosphoribosyl transferase (HGXPRT) can protect mice against Plasmodium yoelii pRBC challenge in a T cell-dependent manner and has, therefore, been proposed as a novel vaccine candidate. It is not known whether natural e...

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Detalles Bibliográficos
Main Authors: Woodberry, Tonia, Pinzon-Charry, Alberto, Piera, Kim A, Panpisutchai, Yawalak, Engwerda, Christian R, Doolan, Denise L, Salwati, Ervi, Kenangalem, Enny, Tjitra, Emiliana, Price, Ric N, Good, Michael F, Anstey, Nicholas M
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2009
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Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2700129/
https://ncbi.nlm.nih.gov/pubmed/19500406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-8-122
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