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The Effects of Load on E-Selectin Bond Rupture and Bond Formation
Molecular dissociation rates have long been known to be sensitive to applied force. We use a laser trap to provide evidence that rates of association may also be force-dependent. We use the thermal fluctuation assay to study single bonds between E-selectin and sialyl Lewis(a) (sLe(a)), the sugar on...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2880517/ https://ncbi.nlm.nih.gov/pubmed/20526425 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12195-010-0110-6 |
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