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Regulation of transferrin receptor expression and ferritin content in human mononuclear phagocytes. Coordinate upregulation by iron transferrin and downregulation by interferon gamma.

We have investigated the regulation of key human iron binding proteins in mononuclear phagocytes by IFN gamma and iron transferrin. In a previous study, we demonstrated that IFN gamma downregulates the expression on human monocytes of transferrin receptors, the major source of iron for the cell. In...

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Xehetasun bibliografikoak
Argitaratua izan da:J Clin Invest
Egile Nagusiak: Byrd, T F, Horwitz, M A
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 1993
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC288049/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8450071/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116318
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