Promotion of variant human mammary epithelial cell outgrowth by ionizing radiation: an agent-based model supported by in vitro studies

INTRODUCTION: Most human mammary epithelial cells (HMEC) cultured from histologically normal breast tissues enter a senescent state termed stasis after 5 to 20 population doublings. These senescent cells display increased size, contain senescence associated β-galactosidase activity, and express cycl...

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Bibliografiske detaljer
Main Authors: Mukhopadhyay, Rituparna, Costes, Sylvain V, Bazarov, Alexey V, Hines, William C, Barcellos-Hoff, Mary Helen, Yaswen, Paul
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2010
Fag:
Research article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2880432/
https://ncbi.nlm.nih.gov/pubmed/20146798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr2477
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