Enhancement of L-3-hydroxybutyryl-CoA dehydrogenase activity and circulating ketone body levels by pantethine. Relevance to dopaminergic injury

BACKGROUND: The administration of the ketone bodies hydroxybutyrate and acetoacetate is known to exert a protective effect against metabolic disorders associated with cerebral pathologies. This suggests that the enhancement of their endogenous production might be a rational therapeutic approach. Ket...

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Autores principales: Cornille, Emilie, Abou-Hamdan, Mhamad, Khrestchatisky, Michel, Nieoullon, André, de Reggi, Max, Gharib, Bouchra
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2010
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Research article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2880308/
https://ncbi.nlm.nih.gov/pubmed/20416081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-11-51
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